
@article{ref1,
title="Lethal suicidal intoxication with propafenone, after a history of self-inflicted injuries",
journal="Forensic science international",
year="1997",
author="Maxeiner, H. and Klug, E.",
volume="89",
number="1-2",
pages="27-32",
abstract="Report of a suicidal mono-intoxication with the class IC antiarrythmic drug propafenone. A 20-year-old female physician's assistant secretly ingested the substance (presumably 20 tablets per 300 mg) about 4-6 h before her death, and in the interim remained under the supervision of her physician. An ECG taken about 1/2-2 h after ingestion showed widening of the QRS complex and signs of an acute load of the right ventricle; the clinical symptoms were nausea, vomiting and hypotonia. After about 4 h without serious symptoms acute loss of consciousness and cardiac failure occurred, resuscitation efforts remained unsuccessful. At autopsy propafenone was found in blood (12 micrograms ml-1), liver (60 micrograms g-1) and cardiac muscle (11 micrograms g-1).<p /><p>Language: en</p>",
language="en",
issn="0379-0738",
doi="",
url="http://dx.doi.org/"
}