@article{ref1,
title="Ethanol and pentobarbital: comparison of behavioral and subjective effects in sedative drug abusers",
journal="Experimental and clinical psychopharmacology",
year="1997",
author="Mintzer, M. Z. and Guarino, J. and Kirk, T. and Roache, John D. and Griffiths, Roland R.",
volume="5",
number="3",
pages="203-215",
abstract="The behavioral and subjective effects of acute oral doses of placebo, ethanol (0.5, 1.0, and 2.0 g/kg), and pentobarbital (150, 300, 600, and 750 mg/70 kg) were compared in 8 male volunteers with histories of sedative drug abuse using a double-blind, double-dummy, cross-over design. Ethanol and pentobarbital produced similar dose-related decrements in psychomotor and cognitive performance and exhibited a similar profile of effects on staff- and participant-rated measures. There was some evidence indicating that, at the highest dose, pentobarbital was perceived by participants as being more sedating than ethanol and that pentobarbital has a greater abuse liability than ethanol. In conjunction with the results of previous human laboratory studies comparing the effects of different types of sedative-hypnotic drugs, these results support a mostly barbiturate-like rather than benzodiazepine-like profile of effects for ethanol.<p /><p>Language: en</p>",
language="en",
issn="1064-1297",
doi="",
url="http://dx.doi.org/"
}