@article{ref1,
title="Tryptophan depletion increases aggression in women during the premenstrual phase",
journal="Psychopharmacology",
year="2001",
author="Bond, Alyson J. and Wingrove, J. and Critchlow, D. G.",
volume="156",
number="4",
pages="477-480",
abstract="RATIONALE: Reducing serotonin by the method of tryptophan depletion (TD) has led to increased aggression but experimental studies have not used female subjects. OBJECTIVE: To evaluate the effects of TD on aggression in women in the late luteal phase of their menstrual cycle. METHODS: Healthy women were recruited and randomly assigned to an amino acid drink either depleted or with a balanced amount of tryptophan. At 4.5 h later, they competed on the competitive reaction time task. RESULTS: Women who had received the TD drink showed more behavioural aggression in response to provocation. CONCLUSION: Decreased serotonergic neurotransmission increases aggression in women as well as men.<p /><p>Language: en</p>",
language="en",
issn="0033-3158",
doi="",
url="http://dx.doi.org/"
}