@article{ref1,
title="Zuclopenthixol in adults with intellectual disabilities and aggressive behaviours: discontinuation study",
journal="British journal of psychiatry",
year="2007",
author="Haessler, Frank and Glaser, Thomas and Beneke, Manfred and Pap, Akos F. and Bodenschatz, Ralf and Reis, Olaf",
volume="190",
number="",
pages="447-448",
abstract="We investigated the effects of zuclopenthixol on aggressive behaviour in patients with intellectual disabilities by randomly withdrawing it after a 6-week period of open treatment. Of the 49 patients responding to the treatment, 39 took part in a randomised withdrawal trial. The placebo subgroup (n=20) showed more aggressive behaviour as indicated by outcomes observed by external raters on the Modified Overt Aggression Scale than did the continuing subgroup (n=19). The results indicate that discontinuation of zuclopenthixolin this population leads to an increase in aggressive behaviour.<p /><p>Language: en</p>",
language="en",
issn="0007-1250",
doi="10.1192/bjp.bp.105.016535",
url="http://dx.doi.org/10.1192/bjp.bp.105.016535"
}