@article{ref1,
title="Psychotic disorder and focal epilepsy in a left-handed patient with chromosome XYY abnormality",
journal="Genetic counseling",
year="2008",
author="Verri, A. P. and Galimberti, C. A. and Perucca, P. and Cremante, A. and Vernice, M. and Uggetti, A.",
volume="19",
number="4",
pages="373-379",
abstract="OBJECTIVE: To discuss the relationship between XYY chromosome abnormality, psychiatric disorders and epilepsy. METHOD: Single case report. RESULTS: A 34-year-old man with 47, XYY karyotype and normal intelligence was followed-up at a neuropsychiatric clinic for over 30 years. He was first seen at age 3 years with a history of delayed motor and language development and an immunodeficiency syndrome. At age 8 years he developed refractory focal epilepsy, and in late adolescence he started to exhibit increasingly prominent obsessive thoughts, paranoid ideation, and aggressive sexual fantasies and behaviour. CONCLUSIONS: When interpreted within the context of previous literature reports, this case suggests a pathophysiological link between XYY chromosome abnormality, characteristic psychiatric symptoms and epilepsy disorder.<p /><p>Language: en</p>",
language="en",
issn="1015-8146",
doi="",
url="http://dx.doi.org/"
}