
@article{ref1,
title="Cerebral uric acid increases following experimental traumatic brain injury in rat",
journal="Brain research",
year="1996",
author="Tayag, E. C. and Nair, S. N. and Wahhab, S. and Katsetos, C. D. and Lighthall, J. W. and Lehmann, J. C.",
volume="733",
number="2",
pages="287-291",
abstract="Following traumatic brain injury (TBI), cortical and thalamic areas were analyzed histologically and by high-performance liquid chromatography with electrochemical detection for uric acid at various survival times. Following TBI, cortical uric acid was elevated by ten-fold at 24 and 48 h, but not at 1 h post-TBI. Histological evidence of neurodegeneration was found not only in cortex but also in the anteroventral thalamus. These data suggest that as in stroke, uric acid measurements may be a convenient and sensitive method for measuring peroxidative status in TBI.<p /><p>Language: en</p>",
language="en",
issn="0006-8993",
doi="",
url="http://dx.doi.org/"
}