@article{ref1,
title="Psychotic illness after prenatal exposure to the 1953 Dutch Flood Disaster",
journal="Schizophrenia Research",
year="1999",
author="Selten, J. P. and van der Graaf, Y. and van Duursen, R. and Gispen-de Wied, C. C. and Kahn, R. S.",
volume="35",
number="3",
pages="243-245",
abstract="We tested the hypothesis that maternal stress during pregnancy increases the risk of non-affective psychosis for the child. The concept of non-affective psychosis includes the ICD categories schizophrenic disorder, paranoid state and other non-organic psychosis. Data from the Dutch Psychiatric Registry were examined for an effect of the Flood Disaster of 1 February 1953. On this day, a gale caused a flood in the South-west of The Netherlands and 1835 people perished. Our study concerned the 19 villages where mortality exceeded 0.25%. The risk of non-affective psychosis for the cohort born in the period February-October 1953 was compared to the risks for the cohorts born in the corresponding periods of the previous and subsequent 2 years. The relative risk of non-affective psychosis for those exposed during gestation was 1.8 [95% Confidence Interval (CI): 0.9-3.5]. Thus, our study failed to demonstrate a significant association between prenatal exposure to maternal stress and risk of non-affective psychosis. The possible explanations for this finding are discussed.<p /><p>Language: en</p>",
language="en",
issn="0920-9964",
doi="",
url="http://dx.doi.org/"
}