@article{ref1,
title="Ipsapirone neuroendocrine challenge: relationship to aggression as measured in the human laboratory",
journal="Psychiatry research",
year="1998",
author="Moeller, F. G. and Allen, T. and Cherek, D. R. and Dougherty, D. M. and Lane, S. and Swann, A. C.",
volume="81",
number="1",
pages="31-38",
abstract="Thirty-one human subjects were administered a neuroendocrine challenge with the 5-HT1a agonist ipsapirone after completing six sessions of a laboratory measure of aggression, the Point Subtraction Aggression Paradigm (PSAP), in order to determine if a laboratory measure of aggression was related to serotonin function. Subjects who showed more aggressive responding on the PSAP (n = 11) had a significantly blunted temperature response to ipsapirone compared to those with less aggressive responding (n = 20). There was no difference between the two groups on the cortisol response to ipsapirone. This study supports a relationship between serotonin function and aggression as measured in the human laboratory, similar to the well-documented association between self-reported aggression and serotonin.<p /><p>Language: en</p>",
language="en",
issn="0165-1781",
doi="",
url="http://dx.doi.org/"
}