@article{ref1,
title="Secondary cerebral stress of systemic origin in children with severe craniocerebral injuries",
journal="Annales Francaises d'Anesthesie et de Reanimation",
year="1998",
author="Marescal, C. and Adnet, P. and Bello, N. and Halle, I. and Forget, A. P. and Boittiaux, P.",
volume="17",
number="3",
pages="234-239",
abstract="OBJECTIVE: To assess incidence of secondary brain insults of systemic origin (SBISOs) such as arterial hypotension, hypoxaemia, hypercarbia, and anaemia in severely head injured children; to assess their impact on mortality and morbidity in the short- and long-term. STUDY DESIGN: Prospective, open study covering a 24-month period. PATIENTS: Seventy-one children, under 15 years of age, admitted to a trauma centre for severe brain injury. METHOD: Analysis of SBISOs and outcome. RESULTS: Twenty-five children were admitted with SBISOs. The mortality rate was 37%. After hospitalization, 84% of the children with SBISOs vs 46% without SBISOs had severe disability (Glasgow outcome score = 1, 2 and 3). After 1 year, 20 out of the 45 children still alive were contacted. One of the four with SBISOs communicated a bad recovery. Fifteen children without SBISOs presented good recovery: GOS = 4-5, paediatric overall performance category (POPC scale) = 1-2. CONCLUSION: Hypotension was associated with significant increase in mortality (x 3.6) in children with severe head injury. The consequences were worse when anaemia was associated.<p /> <p>Language: fr</p>",
language="fr",
issn="0750-7658",
doi="",
url="http://dx.doi.org/"
}