
@article{ref1,
title="Randomized trial of Internet‐based relapse prevention for partially remitted depression",
journal="Acta psychiatrica Scandinavica",
year="2011",
author="Holländare, F. and Johnsson, S. and Randestad, M. and Tillfors, M. and Carlbring, P. and Andersson, G. and Engström, I.",
volume="124",
number="4",
pages="285-294",
abstract="<p><b>Objective:</b> To investigate whether Internet‐based cognitive behaviour therapy (CBT) can prevent relapse in persons with partially remitted major depression after previous treatment.</p> <p><b>Method:</b> Seventy‐one women and 13 men (<i>N</i> = 84) with partially remitted major depression after treatment were randomly assigned to either 10 weeks of Internet‐based CBT or to a control group. Self‐help material was used in combination with e‐mail contact with a personal therapist. Monthly self‐ratings of depressive symptoms were made, and diagnostic interviews were conducted before and after the treatment period, as well as 6 months later.</p> <p><b>Results:</b> Significantly fewer participants in the CBT group experienced relapse (4/38 or 10.5%) compared with those in the control group (14/37 or 37.8%). The difference in relapse rates between groups occurred early in the study period and was still apparent after 6 months. A trend towards a larger reduction in depressive symptoms was observed at post‐treatment in the participants who received CBT compared with controls. Reduction in depressive symptoms reduced the risk of relapse. A trend towards a higher remission rate was found in the CBT group at the 6 month follow‐up.</p> <p><b>Conclusion:</b> Internet‐based CBT seems promising in preventing relapse in persons with partially remitted major depression after previous treatment.</p><p />",
language="",
issn="0001-690X",
doi="10.1111/j.1600-0447.2011.01698.x",
url="http://dx.doi.org/10.1111/j.1600-0447.2011.01698.x"
}