@article{ref1,
title="Predictors of cortisol and 3-methoxy-4-hydroxyphenylglycol responses in the acute aftermath of rape",
journal="Biological psychiatry",
year="1998",
author="Yehuda, Rachel and Resnick, Heidi S. and Schmeidler, J. and Yang, R. K. and Pitman, R. K.",
volume="43",
number="11",
pages="855-859",
abstract="BACKGROUND: Prospective studies of trauma survivors can provide information about the relationship between rape characteristics and the development of subsequent symptoms. METHODS: The present study examined the relationship of prior assault, rape severity, posttraumatic stress disorder (PTSD) symptoms following rape, and subsequent PTSD diagnosis, to the acute cortisol and 3-methoxy-4-hydroxyphenylglycol (MHPG) response to this traumatic event in 20 women. RESULTS: Women with a history of prior physical or sexual assault showed a significantly attenuated cortisol response to the acute stress of rape compared to women without such a history. MHPG appeared to be associated with injury-related rape characteristics, and symptoms of active avoidance, but not prior history. PTSD status at the 3-month follow-up was predicted by both a prior history of assault and high injury rape, but was not directly predicted by either cortisol or MHPG levels. MHPG and cortisol were not correlated in the sample as a whole, but were correlated among individuals who did not subsequently develop PTSD (p = .04) CONCLUSIONS: The results suggest that different neuroendocrine systems may mediate different components of the response to traumatic stress.<p /><p>Language: en</p>",
language="en",
issn="0006-3223",
doi="",
url="http://dx.doi.org/"
}