@article{ref1,
title="Acute renal failure following snakebite",
journal="American journal of tropical medicine and hygiene",
year="1975",
author="Chugh, K. S. and Aikat, B. K. and Sharma, B. K. and Dash, S. C. and Mathew, M. T. and Das, K. C.",
volume="24",
number="4",
pages="692-697",
abstract="Eight patients with acute renal failure following snakebite were studied. Intravascular hemolysis and disseminated intravascular coagulation contributed to the development of acute renal failure in 6 patients. Direct nephrotoxicity causing acute renal failure is postulated in 2 patients, 1 of whom also revealed evidence of mild, disseminated intravascular coagulation. Three patients had histopathological lesions of acute symmetrical cortical necrosis and 3 had acute tubular necrosis. In 1 patient with acute tubular necrosis, in whom direct nephrotoxicity seemed to be responsible for renal failure, the striking histological feature was a uniform debasement and disappearance of tubular epithelium. In 2 patients with a clinical course of acute tubular necrosis, histological lesions could not be documented. All the 5 patients with acute tubular necrosis regained full recovery of renal function, 3 of them with the help of dialysis and 2 with conservative management. None of the 3 patients with acute cortical necrosis survived in spite of intermittent dialysis therapy.<p /><p>Language: en</p>",
language="en",
issn="0002-9637",
doi="",
url="http://dx.doi.org/"
}