@article{ref1,
title="Change of immunoglobulins and complement factors in patients with self-injurious behaviour",
journal="Acta psychiatrica Scandinavica",
year="2003",
author="Moe, T. J. and Mykletun, A. and Matre, R. and Skovlund, E. and Bassøe, C-f and Dahl, Alv A.",
volume="107",
number="2",
pages="151-154",
abstract="OBJECTIVE: As stress activates the inflammatory response system, and attempted suicide is connected with severe stress, we hypothesized that patients hospitalized for self-injurious behaviour have changed immunocompetence. METHOD: The concentration of immunoglobulins IgG, IgA, IgM, and the complement components C3 and C4 in 73 patients hospitalized for self-injurious behaviour was compared with those of 122 healthy controls. The immunoglobulins and complement were quantified by nephelometric technique. RESULTS: The levels of IgG and IgM were significantly lower, and the complement C3 and C4 were significantly higher in self-injurious patients compared with controls. This was valid in both genders and the effects did not interact with gender. CONCLUSIONS: This controlled study showed that the concentrations of immunoglobulins were reduced and complement components were increased in patients who are admitted to hospital for self-injurious behaviour.<p /><p>Language: en</p>",
language="en",
issn="0001-690X",
doi="",
url="http://dx.doi.org/"
}