@article{ref1,
title="Fatal flecainide intoxication",
journal="Forensic science international",
year="1999",
author="Romain, N. and Giroud, C. and Michaud, K. and Augsburger, M. and Mangin, Patrice",
volume="106",
number="2",
pages="115-123",
abstract="A fatal case attributed to flecainide acetate (Tambocor), a class Ic antiarrythmic drug, is presented. Flecainide was detected by GC/MS in gastric contents, blood and liver as well. The urine analysis revealed the presence of its dealkylated metabolite. Body fluids and tissue concentrations determined by GC/ECD were 7.7 mg/kg in femoral blood, 0.26 mg/kg in bile, 18 mg/kg in liver, 0.17 mg/kg in cerebrospinal fluid, 0.22 mg/kg in brain cortex and 28.9 mg/kg in urine. The total amount of flecainide in gastric contents was about 43 mg. Even taking into account the postmortem redistribution of flecainide, its blood level still remains in the toxic range.<p /><p>Language: en</p>",
language="en",
issn="0379-0738",
doi="",
url="http://dx.doi.org/"
}