@article{ref1,
title="Chemical constituents of Gentianaceae XIX: CNS-depressant effects of swertiamarin",
journal="Journal of pharmaceutical sciences",
year="1976",
author="Bhattacharya, S. K. and Reddy, P. K. and Ghosal, S. and Singh, A. K. and Sharma, P. V.",
volume="65",
number="10",
pages="1547-1549",
abstract="CNS activity of swertiamarin, a secoiridoid glucoside from Swertia chirata, was evaluated. An apparent anomaly, associated with the unanticipated finding that the alcoholic extracts (excluding mangiferin) of S. chirata significantly reversed the mangiferin-induced CNS-stimulating effects in albino mice and rats, was resolved. The results indicate that swertiamarin and mangiferin antagonize each other in vivo and thereby reverse their CNS effects.<p /><p>Language: en</p>",
language="en",
issn="0022-3549",
doi="",
url="http://dx.doi.org/"
}