@article{ref1,
title="Combined initial cyclophosphamide with repeated methylprednisolone pulse therapy for severe paraquat poisoning from dermal exposure",
journal="Journal of toxicology - clinical toxicology",
year="2003",
author="Lin, Nan-Chieh and Lin, Ja-Liang and Lin-Tan, Dan-Tzu and Yu, Chun-Chen",
volume="41",
number="6",
pages="877-881",
abstract="The article presents a patient with severe paraquat poisoning from dermal exposure, who had chemical bums to more than 10% of his body surface area, serum paraquat level 0.13 microg/mL 60 hr after exposure, and severe hypoxemia (PaO2 41.6 mmHg). The patient was successfully treated with combined initial megadoses of cyclophosphamide (15 mg/kg/day, total 2 days) with repeated methylprednisolone pulse therapy (15 mg/kg/day, total 6 days) and continuous dexamethasone administration (5 mg every 8 hr), and recovered completely without sequelae 3 months later. This treatment deserves further investigation in future clinical trials.<p /><p>Language: en</p>",
language="en",
issn="0731-3810",
doi="",
url="http://dx.doi.org/"
}