@article{ref1,
title="Establishment of skin scald model in mice",
journal="Fa Yi Xue Za Zhi",
year="2012",
author="Ren, Peng and Guan, Da-Wei and Zhao, Rui and Ma, Wen-Xiangu and Zhang, Shu-Tao",
volume="28",
number="2",
pages="92-4, 99",
abstract="OBJECTIVE: To establish the model of skin scald in mice for the study of skin thermal injuries. METHODS: After anaesthetization mice were scalded in a 1 cm-diameter circle area on the central dorsum by boiling water at contact times: 10s or 25s. The mice were sacrificed at 1, 3, 5, 7 and 10 days after scald. The skin samples were collected and analyzed by gross and histopathological examinations. RESULTS: Deep II degree thermal injury involving full-thickness skin was observed in the 10s scald group. III degree thermal injury involving full-thickness skin and the dorsal skeletal muscle was observed in the 25 s scald group. CONCLUSION: A mouse skin scald model is established which is stable and can be used on the skin thermal injury in future research.<p /> <p>Language: zh</p>",
language="zh",
issn="1004-5619",
doi="",
url="http://dx.doi.org/"
}