@article{ref1,
title="Hiding in plain sight: Risk factors for REM sleep behavior disorder",
journal="Neurology",
year="2012",
author="Sullivan, Shannon S. and Schenck, Carlos H. and Guilleminault, Christian",
volume="79",
number="5",
pages="402-403",
abstract="REM sleep behavior disorder (RBD) is a parasomnia characterized by loss of normal REM sleep muscle atonia that is usually accompanied by dream enactment.(1) The prevalence of this disorder is unknown, but has been estimated at 0.4%-0.5% among adults. RBD is notable both for its potential for disruption of the sleep milieu by complex and aggressive behaviors with resulting injury, and for its identity as a &quot;preclinical&quot; sign of synuclein-mediated neurodegenerative disease such as Parkinson disease (PD) and dementia with Lewy bodies (DLB). The association with neurodegenerative disease is complex, and some investigators argue that RBD marks a subtype of PD. Until now, the genesis of RBD is most often considered &quot;idiopathic,&quot; with little known of potential risk factors for development other than male sex and age greater than 50 years.<p /> <p>Language: en</p>",
language="en",
issn="0028-3878",
doi="10.1212/WNL.0b013e31825dd3c0",
url="http://dx.doi.org/10.1212/WNL.0b013e31825dd3c0"
}