@article{ref1,
title="Stability of early-phase primary psychotic disorders with concurrent substance use and substance-induced psychosis",
journal="British journal of psychiatry",
year="2007",
author="Caton, Carol L. M. and Hasin, Deborah S. and Shrout, Patrick E. and Drake, Robert E. and Dominguez, Boanerges and First, Michael B. and Samet, Sharon and Schanzer, Bella",
volume="190",
number="",
pages="105-111",
abstract="BACKGROUND: The stability of the diagnostic distinction between a substance-induced psychosis and a primary psychotic disorder co-occurring with substance use is not established. AIMS: To describe DSM-IV diagnostic changes over 1 year and determine the predictive validity of baseline indicators of the substance-induced psychosis v. primary psychosis distinction. METHOD: We conducted a 1-year follow-up study of 319 psychiatric emergency department admissions with diagnoses of early-phase psychosis and substance use comorbidity. RESULTS: Of those with a baseline DSM-IV diagnosis of substance-induced psychosis, 25% had a diagnosis of primary psychosis at follow-up. These patients had poorer premorbid functioning, less insight into psychosis and greater family mental illness than patients with a stable diagnosis of substance-induced psychosis. Reclassifying change cases to primary psychoses on follow-up, key baseline predictors of the primary/substance-induced distinction at 1 year also included greater family history of mental illness in the primary psychosis group. CONCLUSIONS: Further study of substance-induced psychoses should employ neuroscientific and behavioural approaches. Study findings can guide more accurate diagnoses at first treatment.<p /><p>Language: en</p>",
language="en",
issn="0007-1250",
doi="10.1192/bjp.bp.105.015784",
url="http://dx.doi.org/10.1192/bjp.bp.105.015784"
}