
@article{ref1,
title="The thrill can kill: murder by methylation",
journal="Molecular pharmacology",
year="2007",
author="Barik, Sailen",
volume="71",
number="5",
pages="1203-1205",
abstract="Why babies of crack-cocaine mothers develop heart problems has always been a mystery. In this issue of Molecular Pharmacology, Zhang et al. (p. 1319) show that a specific methylation occurs at the protein kinase Cepsilon (PKCepsilon) promoter of the babies born of mother rats exposed to cocaine. This reduces the expression of PKCepsilon, a naturally cardioprotective enzyme, which provides a plausible molecular mechanism for cardiac failure.<p /><p>Language: en</p>",
language="en",
issn="0026-895X",
doi="10.1124/mol.107.035196",
url="http://dx.doi.org/10.1124/mol.107.035196"
}