@article{ref1,
title="The influence of gender on the injury severity, course and outcome of traumatic brain injury",
journal="Brain injury",
year="2012",
author="Renner, Caroline and Hummelsheim, Horst and Kopczak, Anna and Steube, Diethard and Schneider, Harald J. and Schneider, Manfred and Kreitschmann-Andermahr, Ilonka and Jordan, Martina and Uhl, Eberhard and Stalla, Günter K.",
volume="26",
number="11",
pages="1360-1371",
abstract="Objective: To examine the independent association of gender with injury severity, clinical course, pituitary dysfunction and outcome after traumatic brain injury (TBI). Design: Prospective cohort, analysis of a data sub-set collected as part of the nation-wide database 'The Structured Data Assessment of Hypopituitarism after TBI and SAH'. Methods and procedures: Four hundred and twenty-seven patients following TBI were observed from acute care through neurological rehabilitation. Outcome was measured by Glasgow Outcome Scale (GOS), employment status and living situation post-injury. As a secondary outcome measure anterior pituitary function was assessed. Results: There were no differences in injury severity between men and women. Age had a significant effect on the GCS score (p = 0.0295), but gender did not (p = 0.4105). The outcome was equivalent between men and women once corrected for age. Logistic regression revealed that gender had no effect (p = 0.8008), but age (p = 0.0021) and initial injury severity (p = 0.0010) had an effect on the GOS. After correcting for pre-injury living situation and employment only initial injury severity (p = 0.0005) influenced GOS. Pituitary insufficiency was not affected by sex or age. Conclusion: Gender does not seem to influence the course and outcome of TBI. Outcome parameters were affected foremost by initial injury severity and by age, but not by sex.<p /> <p>Language: en</p>",
language="en",
issn="0269-9052",
doi="10.3109/02699052.2012.667592",
url="http://dx.doi.org/10.3109/02699052.2012.667592"
}