@article{ref1,
title="MDMA use and neurocognition: a meta-analytic review",
journal="Psychopharmacology",
year="2007",
author="Kalechstein, Ari D. and De La Garza, Richard and Mahoney, James J. and Fantegrossi, William E. and Newton, Thomas F.",
volume="189",
number="4",
pages="531-537",
abstract="RATIONALE: To determine the association between MDMA misuse and neurocognition using meta-analysis. OBJECTIVE: Separate analyses were conducted based on two sets of inclusion/exclusion criteria. A relatively stringent set required that the subjects be matched on important moderator variables, whereas the other did not. The study participants' performance in the following neurocognitive domains was reviewed: attention/concentration, verbal and nonverbal learning and memory, psychomotor speed and executive systems functioning. RESULTS: In the 11 studies meeting the relatively stringent inclusion/exclusion criteria for this review, MDMA use was associated with neurocognitive deficits in each domain. Similarly, in the 23 studies meeting the relatively lenient inclusion/exclusion criteria for this review, MDMA use was associated with neurocognitive deficits in each domain. Small to medium effect sizes were generally observed. A comparison of the effect sizes across the two sets of analyses did not reveal significant differences. CONCLUSIONS: The findings from this review reveal that MDMA use is associated with neurocognitive deficits. The implications of these findings are discussed.<p /><p>Language: en</p>",
language="en",
issn="0033-3158",
doi="10.1007/s00213-006-0601-2",
url="http://dx.doi.org/10.1007/s00213-006-0601-2"
}