@article{ref1,
title="Acute traumatic spinal cord injuries: Epidemiology and prospects",
journal="Neurochirurgie (Paris)",
year="2012",
author="Lonjon, N. and Perrin, F. E. and Lonjon, M. and Fattal, C. and Segnarbieux, F. and Privat, A. and Bauchet, L.",
volume="58",
number="5",
pages="293-299",
abstract="OBJECTIVE: Specify the epidemiological data on the acute spinal cord injuries and define a group of patients that could benefit from cellular transplantation therapy designed with the aim of repair and regeneration of damaged spinal cord tissues. MATERIAL AND METHODS: Five years monocentric (Gui-de-Chauliac Hospital, Montpellier, France) retrospective analysis of patients suffering from spinal cord injury (SCI). Spinal cord injured-patients, defined as sensory-motor complete, underwent a clinical evaluation following American Spinal Injury Association (ASIA) and functional type 2 Spinal Cord Independence Measure (SCIM2) scorings as well as radiological evaluation through spinal cord magnetic resonance imaging (MRI). RESULTS: One hundred and fifty-seven medical records were reviewed and we selected and re-examined 20 patients with complete thoracic spinal cord lesion. Clinical and radiological evaluations of these patients demonstrated, in 75 % of the cases, an absence of clinical progression after a mean of 49months. Radiological abnormalities were constantly present in the initial (at the admission to hospital) and control (re-evaluation) MRI and no reliable predictive criteria of prognosis had been found. DISCUSSION/CONCLUSION: We compare our results to the literature and discuss advantages and limits of cellular transplantation strategies for these patients.<p /> <p>Language: fr</p>",
language="fr",
issn="0028-3770",
doi="10.1016/j.neuchi.2012.06.003",
url="http://dx.doi.org/10.1016/j.neuchi.2012.06.003"
}