@article{ref1,
title="A review of acetaminophen poisoning",
journal="Critical care clinics",
year="2012",
author="Hodgman, Michael J. and Garrard, Alexander R.",
volume="28",
number="4",
pages="499-516",
abstract="Acetaminophen poisoning remains one of the more common drugs taken in overdose with potentially fatal consequences. Early recognition and prompt treatment with N-acetylcysteine can prevent hepatic injury. With acute overdose, the Rumack-Matthew nomogram is a useful tool to assess risk and guide management. Equally common to acute overdose is the repeated use of excessive amounts of acetaminophen. Simultaneous ingestion of several different acetaminophen-containing products may result in excessive dosage. These patients also benefit from N-acetylcysteine. Standard courses of N-acetylcysteine may need to be extended in patients with persistently elevated plasma concentrations of acetaminophen or with signs of hepatic injury.<p /> <p>Language: en</p>",
language="en",
issn="0749-0704",
doi="10.1016/j.ccc.2012.07.006",
url="http://dx.doi.org/10.1016/j.ccc.2012.07.006"
}