@article{ref1,
title="Acute indoramin poisoning: a review of 55 cases reported to the Paris poison centre from 1986 t o 2010",
journal="Therapie",
year="2012",
author="Villa, Antoine F. and Tran Hong, Huan and Min Lee, Hwee and Chataigner, Dominique and Garnier, Robert",
volume="67",
number="6",
pages="523-527",
abstract="Authors report a retrospective study of all cases of indoramin-only poisoning notified to the Paris poison Centre from 1986 to 2010. Fifty five cases of indoramin self-poisoning were included: 40 adults and 15 children. The mean supposed ingested dose was about 701 mg±464 mg. ECG showed a prolonged QTc interval (equal to or greater than 0.50 s) in 30% of patients. The lowest observed dose for prolonged QTc was 625 mg. This series includes two cases of seizures occurring around two hours after ingestion of 900 and 2 250 mg of indoramin. A review of the literature showed cardiac disorders, with a delayed mechanism of action up until 18 hours after ingestion. Therefore, rapid medical resuscitation and prolonged cardiac monitoring for at least 24 hours after ingestion of 625 mg are recommended.<p /> <p>Language: en</p>",
language="en",
issn="0040-5957",
doi="10.2515/therapie/2012075",
url="http://dx.doi.org/10.2515/therapie/2012075"
}