@article{ref1,
title="Cognitive slowing and learning of target detection skills in pre-demented subjects",
journal="Brain and cognition",
year="2004",
author="Amieva, Hélène and Rouch-Leroyer, Isabelle and Letenneur, Luc and Dartigues, Jean-François and Fabrigoule, Colette",
volume="54",
number="3",
pages="212-214",
abstract="Alzheimer's disease produces a generalized slowing of cognitive processing increasing with the progression of dementia. However little is known about this phenomenon in the pre-demented stages. Our purpose was to investigate cognitive slowing in pre-demented subjects and their ability to develop target detection skills while performing a cancellation task. The results on 16 pre-demented subjects and 32 matched controls show that cognitive slowing is already present 3 years before subjects fulfill dementia criteria, at a stage where errors are still not different between pre-demented and control subjects. Additionally, the two groups significantly improved their time performances all along the test suggesting that both groups including the pre-demented group were able to progressively acquire a target detection skill.<p /><p>Language: en</p>",
language="en",
issn="0278-2626",
doi="10.1016/j.bandc.2004.02.003",
url="http://dx.doi.org/10.1016/j.bandc.2004.02.003"
}