@article{ref1,
title="Melancholia: past and present",
journal="Canadian journal of psychiatry, The",
year="2013",
author="Healy, David",
volume="58",
number="4",
pages="190-194",
abstract="Objective: To investigate commonalities in the clinical presentation of melancholia over time. Method: I conducted a comparative study to 2 epidemiologically complete databases from 1875-1924 and 1995-2005. Results: Patients in the historical period (1875-1924, compared with 1995-2005) with a diagnosis of melancholia show a classic profile of endogenous onset, with remission after 6 months, neurovegetative features, and, commonly, psychosis. The incidence of psychotic presentations appears to have fallen in recent decades. Patients in the contemporary period (1995-2010, compared with 1875-1924) at first admission for severe depressive disorders are more likely at an older age, more likely to go on to die by suicide, and will have much more frequent admissions. Conclusions: The data from this study support classical perceptions of melancholia. The poor outcomes in contemporary cases of severe depressive disorders support arguments for distinguishing between melancholia and other depressive disorders.<p /> <p>Language: en</p>",
language="en",
issn="0706-7437",
doi="10.1177/070674371305800403",
url="http://dx.doi.org/10.1177/070674371305800403"
}