@article{ref1,
title="The effect of daily alcohol intake on breath alcohol concentrations of postmenopausal women after a bolus dose",
journal="Journal of studies on alcohol",
year="2003",
author="Novotny, Janet A. and Rumpler, William V. and Baer, David J. and Judd, Joseph T.",
volume="64",
number="3",
pages="380-383",
abstract="OBJECTIVE: This study was designed to test whether daily alcohol intake can influence parameters related to rate of alcohol clearance and systemic alcohol exposure. METHOD: Postmenopausal women (N = 14) completed a study in which they consumed an alcohol treatment daily for 8 weeks. In a three-period crossover design, women consumed 0, 15 or 30 g/day ethanol, with each subject completing each treatment level. Following the 8-week adaptation period, the subjects consumed a single dose of 15 g ethanol, and breath samples collected to assess breath alcohol concentration (BrAC) every 5 minutes until the BrAC declined to zero. RESULTS: Adaptation to daily alcohol intake of 30 g/day resulted in reduced breath alcohol response compared to adaptation to 0 g/day. Specifically, area under the BrAC time curve was lower after women had consumed 30 g ethanol per day compared to that after daily consumption of 0 grams per day. Also, the time required for BrAC to decline to 0.01% after the bolus dose was reduced when subjects were adapted to 30g/day compared to 0 g/day. CONCLUSIONS: Daily intake of alcohol at a level of 30 g/day appears to be sufficient to alter the parameters related to systemic alcohol exposure.<p /><p>Language: en</p>",
language="en",
issn="0096-882X",
doi="",
url="http://dx.doi.org/"
}