@article{ref1,
title="Is there acute tolerance to alcohol at steady state?",
journal="Journal of studies on alcohol",
year="1985",
author="Kaplan, H. L. and Sellers, E. M. and Hamilton, C. and Naranjo, C. A. and Dorian, P.",
volume="46",
number="3",
pages="253-256",
abstract="Although acute tolerance to the psychomotor impairment caused by alcohol has been documented in single-dose studies, the pharmacodynamic effects of continued alcohol administration in humans have not been well studied. Six nonalcoholic men received alcohol to achieve and maintain breath alcohol levels of 80-100 mg/dl for 6 hr. The men suffered an initial impairment in word recall but improved over the next 6 hr. Measures of standing steadiness and manual tracking did not show evidence of the development of tolerance. This lack of tolerance was reflected in subjects' self-assessments of sedation and intoxication.<p /><p>Language: en</p>",
language="en",
issn="0096-882X",
doi="",
url="http://dx.doi.org/"
}