@article{ref1,
title="Sensorimotor and psychosocial determinants of 3-year incident mobility disability in middle-aged and older adults",
journal="Age and ageing",
year="2014",
author="Deshpande, Nandini and Metter, E. Jeffrey and Guralnik, Jack M. and Bandinelli, Stefania and Ferrucci, Luigi",
volume="43",
number="1",
pages="64-69",
abstract="OBJECTIVE: to identify sensorimotor and psychosocial determinants of 3-year incident mobility disability. DESIGN: prospective.   SETTING: population-based sample of community-dwelling older persons.Participants: community-living middle-aged and older persons (age: 50-85 years) without baseline mobility disability (n = 622).   MEASUREMENTS: mobility disability, defined as self-reported inability to walk a quarter mile without resting or inability to walk up a flight of stairs unsupported, was ascertained at baseline and 3-year follow-up. Potential baseline determinant characteristics included demographics, education, social support, financial condition, knee extensor strength, visual contrast sensitivity, cognition, depression, presence of chronic conditions and history of falls.   RESULTS: a total of 13.5% participant reported 3-year incident mobility disability. Age ≥75 years, female sex, knee extensor strength in the lowest quartile, visual contrast sensitivity <1.7 on the Pelli-Robson chart or significant depressive symptoms (CESD score >16) were independent determinants of 3-year incident mobility disability (ORs 1.84-16.51).   CONCLUSIONS: low visual contrast sensitivity, poor knee extensor strength and significant depressive symptoms are independent determinants of future onset of mobility disability.<p /> <p>Language: en</p>",
language="en",
issn="0002-0729",
doi="10.1093/ageing/aft135",
url="http://dx.doi.org/10.1093/ageing/aft135"
}