@article{ref1,
title="Assessment of sleep and circadian rhythm disorders in the very old: The Newcastle 85+ Cohort Study",
journal="Age and ageing",
year="2014",
author="Anderson, Kirstie N. and Catt, Michael and Collerton, Joanna and Davies, Karen and von Zglinicki, Thomas and Kirkwood, Thomas B. L. and Jagger, Carol",
volume="43",
number="1",
pages="57-63",
abstract="OBJECTIVES: to examine the association between subjective and objective measures of sleep and wake and other health parameters in a cohort of the very old. DESIGN: a population-based cohort study. SETTING: primary care, North East England.Participants: four hundred and twenty-one men and women, aged 87-89, recruited to the Newcastle 85+ Study cohort. METHODS: sleep questionnaires were administered and sleep-wake patterns were assessed over 5-7 days with a novel wrist triaxial accelerometer. Associations between sleep measures and various health parameters, including mortality at 24 months, were examined. RESULTS: only 16% of participants perceived their sleep as severely disturbed as assessed with questionnaire responses. Wrist accelerometry showed marked variation between normal and abnormal sleep-wake cycles that did not correlate with the participants' perception of sleep. Impaired sleep-wake cycles were significantly associated with cognitive impairment, disability, depression, increased falls, body mass index and arthritis but not with any other specific disease markers and with decreased survival. CONCLUSIONS: commonly used sleep questionnaires do not differentiate well between those with objectively determined disturbance of sleep-wake cycles and those with normal cycles. Abnormal sleep-wake patterns are associated with institutionalisation, cognitive impairment, disability, depression and arthritis but not with other diseases; there is also an association with reduced survival.<p /> <p>Language: en</p>",
language="en",
issn="0002-0729",
doi="10.1093/ageing/aft153",
url="http://dx.doi.org/10.1093/ageing/aft153"
}