@article{ref1,
title="Parent psychopathology and offspring mental disorders: Results from the WHO World Mental Health Surveys",
journal="British journal of psychiatry",
year="2012",
author="McLaughlin, Katie A. and Gadermann, Anne M. and Hwang, Irving and Sampson, Nancy A. and Al-Hamzawi, Ali and Andrade, Laura Helena and Angermeyer, Matthias C. and Benjet, Corina and Bromet, Evelyn J. and Bruffaerts, Ronny and Caldas-de-Almeida, Jose Miguel and de Girolamo, Giovanni and de Graaf, Ron and Florescu, Silvia E. and Gureje, Oye and Haro, Josep Maria and Hinkov, Hristo Ruskov and Horiguchi, Itsuko and Hu, Chiyi and Karam, Aimee Nasser and Kovess-Masféty, Viviane and Lee, Sing and Murphy, Samuel D. and Nizamie, S. Haque and Posada-Villa, Jose and Williams, Daniel R. and Kessler, Ronald C.",
volume="200",
number="4",
pages="290-299",
abstract="BACKGROUND: Associations between specific parent and offspring mental disorders are likely to have been overestimated in studies that have failed to control for parent comorbidity. AIMS: To examine the associations of parent with respondent disorders. METHOD: Data come from the World Health Organization (WHO) World Mental Health Surveys (n = 51 507). Respondent disorders were assessed with the Composite International Diagnostic Interview and parent disorders with informant-based Family History Research Diagnostic Criteria interviews. RESULTS: Although virtually all parent disorders examined (major depressive, generalised anxiety, panic, substance and antisocial behaviour disorders and suicidality) were significantly associated with offspring disorders in multivariate analyses, little specificity was found. Comorbid parent disorders had significant sub-additive associations with offspring disorders. Population-attributable risk proportions for parent disorders were 12.4% across all offspring disorders, generally higher in high- and upper-middle- than low-/lower-middle-income countries, and consistently higher for behaviour (11.0-19.9%) than other (7.1-14.0%) disorders. CONCLUSIONS: Parent psychopathology is a robust non-specific predictor associated with a substantial proportion of offspring disorders.<p /> <p>Language: en</p>",
language="en",
issn="0007-1250",
doi="10.1192/bjp.bp.111.101253",
url="http://dx.doi.org/10.1192/bjp.bp.111.101253"
}