@article{ref1,
title="Reversal of ethanol intoxication in humans: an assessment of the efficacy of L-dopa, aminophylline, and ephedrine",
journal="Psychopharmacology",
year="1977",
author="Alkana, R. L. and Parker, E. S. and Cohen, H. B. and Birch, H. and Noble, Ernest P.",
volume="55",
number="3",
pages="203-212",
abstract="The effect of postethanol treatment with L-Dopa, aminophylline and/or ephedrine was investigated. In one experiment, healthy, male, moderate drinkers ingested ethanol (0.8 g/kg) and then either L-Dopa (1.5 g), or placebo. In a second experiment, subjects ingested ethanol followed by aminophylline (200 mg), ephedrine (50 mg), aminophylline (200 mg) plus ephedrine (50 mg), or placebo. Double-blind, within-subjects, crossover designs were employed. Treatment with L-Dopa significantly reduced ethanol's effect on the electroencephalogram, motor coordination, and divided attention performance (t-test for paired data). Treatment with aminophylline and/or ephedrine also significantly reduced ethanol's effects on the electroencephalogram and motor coordination. The ethanol-antagonism may result from central noradrenergic stimulation.<p /><p>Language: en</p>",
language="en",
issn="0033-3158",
doi="",
url="http://dx.doi.org/"
}