@article{ref1,
title="Heritability of DUI convictions: A twin study of driving under the influence of alcohol",
journal="Twin research and human genetics",
year="2014",
author="Anum, Emmanuel A. and Silberg, Judy and Retchin, Sheldon M.",
volume="17",
number="1",
pages="10-15",
abstract="BACKGROUND: The study was undertaken to assess the relative contributions of genetic and environmental influences on drunk-driving.   METHODS: Driving records of a cohort of male and female twins (N = 17,360) from the Mid-Atlantic Twin Registry were examined. Structural equation models were used to estimate the magnitude of genetic and environmental effects on male and female phenotypes, and test for gender differences.   RESULTS: There were significant gender and age effects. Compared with females, males were five times more likely to engage in driving under the influence. Among persons aged 21-49 years, the risk for drunk-driving was eight times that for those aged 50+ years and five times greater than those ≤20 years. In both males and females, aged 21-49 years, a large proportion (57%) of the variance in drunk-driving was due to genetic factors and the remaining 43% due to individual specific environmental influences.   CONCLUSIONS: Drunk-driving is under significant genetic influence in both males and females. Our findings suggest that a different set of genes influence DUIs in men and women.<p /> <p>Language: en</p>",
language="en",
issn="1832-4274",
doi="10.1017/thg.2013.86",
url="http://dx.doi.org/10.1017/thg.2013.86"
}