@article{ref1,
title="Depressive disorders in long-term survivors of stroke. Associations with demographic and social factors, functional status, and brain lesion volume",
journal="British journal of psychiatry",
year="1994",
author="Sharpe, M. and Hawton, Keith E. and Seagroatt, V. and Bamford, J. and House, A. and Molyneux, A. and Sandercock, P. and Warlow, C.",
volume="164",
number="3",
pages="380-386",
abstract="Sixty surviving patients from a community-based stroke register who had computerised tomography (CT) scan evidence of a single brain lesion were interviewed three to five years after their first ever stroke. Depression (DSM-III-R major depression, partially resolved major depression, and dysthymia) was present in 11 (18%) of the patients and was associated with impaired physical and cognitive functioning, greater age, residence in an institution, absence of a close personal relationship, and larger original brain lesion. Of these variables, only functional dependence (odds ratio 16.4; confidence interval 1.6-170), larger lesion volume (6.6; 1-50), and female sex (8; 1.1-56) remained significantly associated with depression after controlling for all other variables. We conclude that depression in long-term survivors of stroke has many of the same associations as depression in non-stroke elderly populations. Depression in long-term stroke survivors may also be associated with larger original brain lesions, although this requires confirmation in a prospective study.<p /><p>Language: en</p>",
language="en",
issn="0007-1250",
doi="",
url="http://dx.doi.org/"
}