@article{ref1,
title="Does dual diagnosis affect violence and moderate/superficial self-harm in heroin addiction at treatment entry?",
journal="Journal of addiction medicine",
year="2014",
author="Maremmani, Angelo Giovanni Icro and Rugani, Fabio and Bacciardi, Silvia and Rovai, Luca and Pacini, Matteo and Dellʼosso, Liliana and Maremmani, Icro",
volume="8",
number="2",
pages="116-122",
abstract="OBJECTIVES:: The presence of aggressive and self-harm behaviors is common in heroin-addicted patients, but these frequent co-occurrences have been poorly investigated. Given the fact that self-harm may be seen as both a clear addictive behavior, with its opiate theory, and as part of psychiatric illness, such as psychosis and bipolar spectrum disorders, in this study, we intend to investigate which of the 2 models is more consistent. METHODS:: We compared dual diagnosis with the clinical features of 30 moderate/superficial self-harmed and 162 violent heroin-addicted patients who reported aggressive behavior in the month preceding their request to be treated. As control group, we selected 808 lifetime nonviolent heroin-addicted patients. RESULTS:: The presence of a bipolar spectrum diagnosis proved to be the highest risk factor (B = 4.33; exp(B) = 76.52; 95% confidence interval for exp(B) = 35.69-164.04; P < 0.001) for the presence of aggressive behavior (χ = 433.05; df = 5; P < 0.001). The highest risk factor for the presence of moderate/superficial self-harm (χ = 24.83; df = 2; P < 0.001) was a dual diagnosis for chronic psychosis (β = 1.46; exp(B) = 4.34); 95% confidence interval for exp(B) = 1.11-16.98; P < 0.001). The relationships between aggressive and/or self-harm behaviors and the natural history of addiction in heroin-addicted patients seemed to be less consistent. CONCLUSIONS:: Our data show a frequent co-occurrence of aggression and bipolar spectrum disorder in heroin-addicted patients, which is manifested as aggression directed toward others (violence). On the contrary, self-injurious behavior seems to be strongly correlated with psychotic disorders. Thus, aggressive behavior seems to be correlated, in heroin-addicted patients before entering treatment, with dual diagnosis rather than with a natural history of heroin addiction.<p /> <p>Language: en</p>",
language="en",
issn="1932-0620",
doi="10.1097/ADM.0000000000000019",
url="http://dx.doi.org/10.1097/ADM.0000000000000019"
}