@article{ref1,
title="Central therapeutic effects of dihydroderivative of pralidoxime (pro-2-PAM) in organophosphate intoxication",
journal="Archives Internationales de Pharmacodynamie et de Therapie",
year="1978",
author="Rump, S. and Faff, J. and Borkowska, G. and Ilczuk, I. and Rabsztyn, T.",
volume="232",
number="2",
pages="321-332",
abstract="Central actions of pro-2-PAM (dihydroderivative of 2-PAM) and 2-PAM in poisonings with DFP have been studied. It was shown that pro-2-PAM significantly increased activity of DFP inhibited acetylcholinesterase in the brain, quickly ceased the DFP-induced paralysis of respiration, partially normalized the DFP-induced abnormalities in electrocorticogram and increased the convulsive dosis of DFP. Effects of 2-PAM in these experiments were negligible.<p /><p>Language: en</p>",
language="en",
issn="0003-9780",
doi="",
url="http://dx.doi.org/"
}