@article{ref1,
title="An examination of 1-year adherence and persistence rates to antiepileptic medication in children with newly diagnosed epilepsy",
journal="Journal of pediatric psychology",
year="2014",
author="Aylward, Brandon S. and Rausch, Joseph R. and Modi, Avani C.",
volume="40",
number="1",
pages="66-74",
abstract="OBJECTIVE: The primary aim of the current study was to use new methods to examine 1-year quality of medication dosing (adherence) and continuation with medication treatment (persistence) rates to antiepileptic drugs (AEDs) in children with newly diagnosed epilepsy. <br><br>METHODS: Medication-taking behaviors of AEDs were assessed using electronic monitors for 117 children with newly diagnosed epilepsy for the first year after diagnosis. <br><br>RESULTS: Approximately 15% of participants were categorized as nonpersistent (i.e., failed to take medication for >15 consecutive days) 6-months after AED initiation, which increased to 26.6% of participants at 1 year. The majority of medication dosing events took place within a +/-2-hr interval as recommended. The group with lower socioeconomic status demonstrated more nonpersistence over time. <br><br>CONCLUSION: Examining adherence and persistence in medication taking behaviors may yield different types of data for clinical and research purposes.<p /> <p>Language: en</p>",
language="en",
issn="0146-8693",
doi="10.1093/jpepsy/jsu010",
url="http://dx.doi.org/10.1093/jpepsy/jsu010"
}