@article{ref1,
title="Effects of exercise in the heat on predisposition to heatstroke",
journal="Medicine and science in sports",
year="1979",
author="Hubbard, R. W.",
volume="11",
number="1",
pages="66-71",
abstract="This article reviews briefly the historical origins for both the cardiovascular and neural-anhidrotic concepts of heatstroke pathophysiology. It describes how deemphasis of the role of anhidrosis as the primary cause of heatstroke has resulted in: (a) an increased acceptance of animal models for heatstroke research; (b) further evidence that rigid reliance on the classic heatstroke symptoms (coma, anhidrosis, and a fever over 106 degrees F) can result in underdiagnosis; and (c) new research consistant with the hypothesis that exhaustive physical effort, by worsening circulatory collapse and metabolic acidosis predisposes tissue to hyperthermic injury and, as a result, substantially lowers the threshold for heatstroke injury and mortality. Thus, a new hypothesis combining the essential features of both direct thermal injury and cardiovascular origins of heatstroke pathophysiology may be necessary.<p /><p>Language: en</p>",
language="en",
issn="0025-7990",
doi="",
url="http://dx.doi.org/"
}