@article{ref1,
title="Regional ethanol absorption of the human brain during the influx phase measured by means of the magnetic resonance spectroscopy (MRS) and positron emission tomography (PET)",
journal="Blutalkohol",
year="2002",
author="Amberg, R and Furmaier, R and Hirt, H and Urban, R.",
volume="39",
number="2",
pages="61-71",
abstract="In four cases the local brain ethanol concentrations were investigated by means of magnetic resonance spectroscopy in vivo after intra venous application of 0.4-0.6 ethanol/kg body mass. It was observed that there were different brain ethanol concentrations in different parts of the brain - in the basal ganglia, the Para ventricular region and the cerebellum - during ethanol influx with time intervals of 5 minutes, measured at time spans of approximately 6 minutes. The results were confirmed by PET investigation after continuous infusion and bolus injection of 1 lc labelled ethanol at time intervals of 6 to 40 minutes. The possible reasons for this initial uneven distribution in the brain are discussed on the basis of literature on animal experiments and associated studies of ethanol and receptor complexes of the GABA-BZ-receptor and the NMDA-receptor systems.<p />",
language="de",
issn="0006-5250",
doi="",
url="http://dx.doi.org/"
}