@article{ref1,
title="Biphasic time-course of alcohol-induced changes in electrodermal activation parameters",
journal="Blutalkohol",
year="1977",
author="Richter, R. and Kielholz, P. and Hobi, V.",
volume="14",
number="5",
pages="279-291",
abstract="Alcohol-induced changes in activation have been investigated following the time-course of blood-alcohol concentrations. A single dose of 0.77 g/kg alcohol (vodka) was administered to 16 healthy men (mean age 36.9 years) serving as their own controls in a change-over design. To measure the CNS-activation level, two variables of electrodermal activity - the spontaneous fluctuation frequency and the skin resistance response - were used as indicators of habituation of the orienting response to an acoustic stimulus. In both variables the authors found a biphasic time-course of the alcohol effect upon the activation level, i.e. increased activation up to 60 min (the absorption phase), and well-known decreased activation in the post-absorption phase. It has been supposed that this biphasic effect is due to two relatively separable processes, which constitute by their phase-shifted antagonism the demonstrated effect, i.e. increased nonspecific tonic activation in the absorption phase and decreased specific phasic activation in the post-absorption phase.<p />",
language="de",
issn="0006-5250",
doi="",
url="http://dx.doi.org/"
}