@article{ref1,
title="Biphasic effects of alcohol drinking on methamphetamine metabolism in man",
journal="Alcohol and alcoholism",
year="1988",
author="Shimosato, K. and Oda, H. and Ohmae, M. and Tomita, M. and Doi, Y.",
volume="23",
number="5",
pages="351-357",
abstract="In methamphetamine (MAP) addicts, long-term ethanol ingestion 3-4 times per week induced an increased rate of p-hydroxylation of MAP and amphetamine (AMP). Simultaneous ingestion of ethanol and MAP inhibited both p-hydroxylation of MAP and AMP and N-demethylation of MAP in inebriated addicts. The p-hydroxylation of MAP and AMP was also significantly inhibited in daily drinkers despite the almost total absence of urinary ethanol. This suggests that the intensity of MAP-induced behavioral and psychological effects in MAP addicts may, in part, depend upon their drinking habits.<p /><p>Language: en</p>",
language="en",
issn="0735-0414",
doi="",
url="http://dx.doi.org/"
}