@article{ref1,
title="Current and emerging technology in G-LOC detection: noninvasive monitoring of cerebral microcirculation using near infrared",
journal="Aviation, space, and environmental medicine",
year="1988",
author="Glaister, D. H.",
volume="59",
number="1",
pages="23-28",
abstract="G-induced loss of consciousness (G-LOC) has emerged as an important operational problem of high-performance aircraft. Since it appears that G-LOC will continue to be a problem, a requirement exists to detect its occurrence in pilots so that the aircraft may be placed on autopilot. One excellent method of detecting G-LOC physiologically, one would assume, would be based on the oxidative status of the brain. This determination can be made noninvasively with an Oxidative Metabolism Near-Infrared monitor using 4 wave lengths (OMNI-4). The OMNI-4 is capable of measuring the relative quantities in the brain of hemoglobin (Hb), oxygenated hemoglobin (HbO2), blood volume (BV), and oxidative status of cytochrome c oxidase. This instrument was tested on subjects in the USAFSAM human-use centrifuge at +3, 4, and 5 Gz with onset rates of 1 G.s-1. <br><br>RESULTS showed changes within the brain, as expected, during increased G with reductions in Hb, BV, and HbO2. Cytochrome c oxidase measurements were inconclusive. Immediately following G exposure, Hb, BV, and HbO2 &quot;overshoots&quot; occurred suggesting vasodilation of the cerebral microcirculation. The use of OMNI-4 in the laboratory and its possible role as a detector of G-LOC in pilots are discussed including suggestions for future developments.<p /><p>Language: en</p>",
language="en",
issn="0095-6562",
doi="",
url="http://dx.doi.org/"
}