@article{ref1,
title="Post-dexamethasone cortisol, self-inflicted injury, and suicidal ideation among depressed adolescent girls",
journal="Journal of abnormal child psychology",
year="2014",
author="Beauchaine, Theodore P. and Crowell, Sheila E. and Hsiao, Ray C.",
volume="43",
number="4",
pages="619-632",
abstract="Although the dexamethasone suppression test (DST) has limited use as a biomarker of depression given inadequate sensitivity and specificity, it marks prospective risk for suicide among adults. However, few studies have examined associations between the DST, suicidal ideation, and self-inflicted injury (SII) among adolescents, even though SII is the single best predictor of eventual suicide. We evaluated the DST as a correlate of suicidal ideation and retrospective reports of self-inflicted injury (SII) among adolescent girls, ages 13-17, with histories of depression (n = 28) or depression and self-harm (n = 29). Lower post-DST cortisol was associated with suicidal ideation and SII, over-and-above parent-reports and combined parent-/self-reports of internalizing and externalizing behavior. These findings are consistent with recent acquired capacity models of stress-related psychopathology in which hypothalamic-pituitary adrenal (HPA) axis function is altered through epigenetic/allostatic mechanisms among vulnerable individuals who incur adversity early in life.<p /> <p>Language: en</p>",
language="en",
issn="0091-0627",
doi="10.1007/s10802-014-9933-2",
url="http://dx.doi.org/10.1007/s10802-014-9933-2"
}