@article{ref1,
title="Re-examining premature mortality in anorexia nervosa: A meta-analysis redux",
journal="Comprehensive psychiatry",
year="2014",
author="Keshaviah, Aparna and Edkins, Katherine and Hastings, Elizabeth R. and Krishna, Meera and Franko, Debra L. and Herzog, David B. and Thomas, Jennifer J. and Murray, Helen B. and Eddy, Kamryn T.",
volume="55",
number="8",
pages="1773-1784",
abstract="Anorexia nervosa (AN) is reported to have the highest premature mortality of any psychiatric disorder, but recent meta-analyses may have inflated estimates. We sought to re-estimate mortality after methodological corrections and to identify predictors of mortality. We included 41 cohorts from 40 peer-reviewed studies published between 1966 and 2010. <br><br>METHODS included double data extraction, log-linear regression with an over-dispersed Poisson model, and all-cause and suicide-specific standardized mortality ratios (SMRs), with 95% Poisson confidence intervals. Participants with AN were 5.2 [3.7-7.5] times more likely to die prematurely from any cause, and 18.1 [11.5-28.7] times more likely to die by suicide than 15-34year old females in the general population. Our estimates were 10% and 49% lower, respectively, than previously reported SMRs. Risk of premature mortality was highest in studies with older participants, although confounding by treatment was present. Gender, ascertainment, and diagnostic criteria also impacted risk.<p /><p>Language: en</p>",
language="en",
issn="0010-440X",
doi="10.1016/j.comppsych.2014.07.017",
url="http://dx.doi.org/10.1016/j.comppsych.2014.07.017"
}