@article{ref1,
title="Effects of vitamin D in the elderly population: current status and perspectives",
journal="Archives of public health",
year="2014",
author="Bruyere, Olivier and Cavalier, Etienne and Souberbielle, Jean-Claude and Bischoff-Ferrari, Heike A. and Beaudart, Charlotte and Buckinx, Fanny and Reginster, Jean-Yves and Rizzoli, René",
volume="72",
number="1",
pages="32-32",
abstract="Besides its well-known effect on bone metabolism, recent researches suggest that vitamin D may also play a role in the muscular, immune, endocrine, and central nervous systems. Double-blind RCTs support vitamin D supplementation at a dose of 800 IU per day for the prevention of falls and fractures in the senior population. Ecological, case-control and cohort studies have suggested that high vitamin D levels were associated with a reduced risk of autoimmune diseases, type 2 diabetes, cardio-vascular diseases and cancer but large clinical trials are lacking today to provide solid evidence of a vitamin D benefit beyond bone health. At last, the optimal dose, route of administration, dosing interval and duration of vitamin D supplementation at a specific target dose beyond the prevention of vitamin D deficiency need to be further investigated.<p /> <p>Language: en</p>",
language="en",
issn="0778-7367",
doi="10.1186/2049-3258-72-32",
url="http://dx.doi.org/10.1186/2049-3258-72-32"
}