@article{ref1,
title="Clinical application of a new enzyme-linked assay for the estimation of brain-specific creatine kinase in head injured patients",
journal="British journal of neurosurgery",
year="1989",
author="Curley, P. and Abbott, R. and Vallance, D.",
volume="3",
number="6",
pages="655-658",
abstract="The clinical value of serum brain specific creatine kinase (CK-BB) was assessed in head injured patients (group A) using a new enzyme-linked immunosorbent assay (ELISA). The results were compared to healthy controls (group B) and patients post-myocardial infarction (group C). None of the head injured patients had undergone a surgical procedure or ventricular puncture. CK-BB was significantly higher in group A than in controls. The level of CK-BB in group A was inversely proportional to the Glasgow Coma Scale on admission. All patients with a CK-BB greater than 100 micrograms/l died. The ELISA technique is a simple and reliable assay with prognostic significance in patients with head injury and has wider clinical application than the previously described radioimmunoassay methods.<p /><p>Language: en</p>",
language="en",
issn="0268-8697",
doi="",
url="http://dx.doi.org/"
}