@article{ref1,
title="Radiation cataract following injection of radium 224",
journal="Fortschritte der Ophthalmologie",
year="1989",
author="Stefani, F. H. and Mays, C. W. and Spiess, H.",
volume="86",
number="1",
pages="32-37",
abstract="The Spiess Ra-224 series ist presented. It consists of 900 patients who were repeatedly injected intravenously with known dosages (microCi/kg) of the alpha-particle emitter Ra-224 for the intended treatment of tuberculosis and ankylosing spondylitis between 1943 and 1952/1965. 682 patients had been treated as adults after the age of 20 years, and 218 hat been injected as &quot;juveniles&quot; aged 20 years or younger. All 218 &quot;juvenile&quot; patients except one who had suffered from ankylosing spondylitis, had been injected for tuberculosis. Among the 218 patients 91 have died leaving 127 alive. Of the &quot;juvenile&quot; patients 9 were examined at the Eye Hospital of the Universität München including histopathology of an autopsy eye in one case. Of the 9 patients 8 proved to have some cataracts and 2 appeared morphologically similar to age-related cataract. In 6 patients there was a posterior subcapsular cataract which was a dense round plaque with a clear subcapsular zone of about 0.5 to 0.6 mm. This clear zone corresponds well to newly deposited lens fibres during the period of about 40 years from treatment to examination.<p /><p>Language: de</p>",
language="de",
issn="0723-8045",
doi="",
url="http://dx.doi.org/"
}