@article{ref1,
title="Non-union of fractures in children who have osteogenesis imperfecta",
journal="Journal of bone and joint surgery: American volume",
year="1988",
author="Gamble, J. G. and Rinsky, L. A. and Strudwick, J. and Bleck, E. E.",
volume="70",
number="3",
pages="439-443",
abstract="Although a fracture rarely fails to unite in a healthy child, non-union is not a rare occurrence in a child who has osteogenesis imperfecta. We identified twelve non-unions in ten patients from a population of fifty-two patients who had osteogenesis imperfecta. The average age of these patients when the diagnosis of non-union was made nine years, and the average age at the time of treatment was 12.5 years. All of the patients had had a decrease in functional ability as a result of the non-union. There were five femoral, four humeral, one radial, one ulnar, and one pubic non-union. Five of the non-unions were hypertrophic, and seven were atrophic. Eight of the nine ununited fractures that were operated on healed after excision of the non-union, intramedullary nailing, and bone-grafting. Three of the non-unions (in two patients) were not operated on, and the one patient in whom surgery failed had an amputation. Non-union was frequently associated with repeated fractures at a progressively deforming site.<p /><p>Language: en</p>",
language="en",
issn="0021-9355",
doi="",
url="http://dx.doi.org/"
}