@article{ref1,
title="Delayed leukoencephalopathy after acute carbon monoxide intoxication",
journal="Journal of radiology case reports",
year="2014",
author="Geraldo, Ana Filipa and Silva, Cristiana and Neutel, Dulce and Neto, Lia Lucas and Albuquerque, Luísa",
volume="8",
number="5",
pages="1-8",
abstract="Delayed leukoencephalopathy is an uncommon complication of hypoxic-ischemic events of different etiologies, including carbon monoxide intoxication. We present a case of a 40-year-old male patient who was admitted with rapidly progressive neurocognitive and behavioral deficits. There was a history of accidental carbon monoxide intoxication one month before, presenting with loss of consciousness and short hospitalization, followed by a complete clinical recovery. The imaging studies in the delayed phase depicted confluent, symmetric supra-tentorial white matter lesions in keeping with diffuse demyelinization. Restricted diffusion and metabolite abnormalities in magnetic resonance proton spectroscopy were also seen. The diagnosis of CO-mediated delayed post-hypoxic leukoencephalopathy was assumed after exclusion of other mimickers. Hyperbaric oxygen therapy was tentatively performed and the patient had a favorable clinical and radiological evolution.<p /> <p>Language: en</p>",
language="en",
issn="1943-0922",
doi="10.3941/jrcr.v8i5.1721",
url="http://dx.doi.org/10.3941/jrcr.v8i5.1721"
}